Hey @B B
Thanks for the follow up! Jumping in for Brian.
You are 100% right, a high unsubscribe rate can negatively impact your sending reputation and overall account health. One thing to consider is the time. Your account health is based on the last 30 days, so if you are worried there will be a lot of unsubscribes, I would suggest creating a few different segments of unengaged profiles (ie 90days, 6months, 1 year) and setup a win-back flow with the most recently engaged profiles first (higher probability for conversion). If this performs well without negatively impacting your deliverability, move on to the next segment and so on until the flow has been sent to each of your segments. If you start to see a negative impact, I would turn the flow off, and only send messaging to your most engaged for while until your deliverability has improved.
You can also put the flow into “manual” mode and moderate how the flow is doing and only move profiles through as you see best for your company, However, this would require more hands on time.
Hope this helps to answer your question more directly.